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ORNL's Communications team works with news media seeking information about the laboratory. Media may use the resources listed below or send questions to news@ornl.gov.
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Researchers have long thought that formation of insoluble fibrous āstringsā of self-assembling proteins might be involved in the progression of a number of diseases, including neurodegenerative disorders such as Alzheimerās and Parkinsonās. However, recent evidence suggests that aggregates that develop at an earlier stage than fibril formation, and accumulate in human organs, may be the primary toxic agents.