91°µÍø

Sometimes solutions to the biggest problems can be found in the smallest details. The work of biochemist Alex Johs at 91°µÍø bears this out, as he focuses on understanding protein structures and molecular interactions to resolve complex global problems like the spread of mercury pollution in waterways and the food supply.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

OAK RIDGE, Tenn., March 20, 2019—Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis.

OAK RIDGE, Tenn., March 4, 2019—A team of researchers from the Department of Energy’s 91°µÍø Health Data Sciences Institute have harnessed the power of artificial intelligence to better match cancer patients with clinical trials.

While studying the genes in poplar trees that control callus formation, scientists at 91°µÍø have uncovered genetic networks at the root of tumor formation in several human cancers.