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Researchers at the Department of Energy’s 91���� have used Summit, the world’s most powerful and smartest supercomputer, to identify 77 small-molecule drug compounds that might warrant further study in the fight

Biological membranes, such as the “walls” of most types of living cells, primarily consist of a double layer of lipids, or “lipid bilayer,” that forms the structure, and a variety of embedded and attached proteins with highly specialized functions, including proteins that rapidly and selectively transport ions and molecules in and out of the cell.

As the second-leading cause of death in the United States, cancer is a public health crisis that afflicts nearly one in two people during their lifetime.

91���� will partner with Cincinnati Children’s Hospital Medical Center to explore ways to deploy expertise in health data science that could more quickly identify patients’ mental health risk factors and aid in

A select group gathered on the morning of Dec. 20 at the Department of Energy’s 91���� for a symposium in honor of Liane B. Russell, the renowned ORNL mammalian geneticist who died in July.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

OAK RIDGE, Tenn., March 20, 2019—Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis.

OAK RIDGE, Tenn., March 4, 2019—A team of researchers from the Department of Energy’s 91���� Health Data Sciences Institute have harnessed the power of artificial intelligence to better match cancer patients with clinical trials.

While studying the genes in poplar trees that control callus formation, scientists at 91���� have uncovered genetic networks at the root of tumor formation in several human cancers.