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The Innovative and Novel Computational Impact on Theory and Experiment, or INCITE, program has announced the 2026 Call for Proposals, inviting researchers to apply for access to some of the world’s most powerful high-performance computing systems. 

Daniel Jacobson, distinguished research scientist in the Biosciences Division at ORNL, has been elected a Fellow of the American Institute for Medical and Biological Engineering, or AIMBE, for his achievements in computational biology. 

Researchers from ORNL have developed a new application to increase efficiency in memory systems for high performance computing. Rather than allow data to bog down traditional memory systems in supercomputers and impact performance, the team from ORNL, along with researchers from the University of Tennessee, Knoxville, created a framework to manage data more efficiently with memory systems that employ more complex structures. 

Scientists at ORNL and the University of Cincinnati achieved a breakthrough in understanding the vulnerability of microbes to the butanol they produce during fermentation of plant biomass. The discovery could pave the way for more efficient production of domestic fuels, chemicals and materials.

In collaboration with the U.S. Department of Homeland Security’s Science and Technology Directorate, researchers at ORNL are evaluating technology to detect compounds emitted by pathogens and pests in agricultural products at the nation’s border. 

Professionals from government and industry gathered at ORNL for the Nondestructive Assay Holdup Measurements Training Course for Nuclear Criticality Safety, a hands-on training in nondestructive assay, a technique for detecting and quantifying holdup without disturbing operations. 

Researchers at Georgia State University used the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision repair. Decoding NER’s sophisticated sequence of events and the role of PInC in the pathway could provide key insights into developing novel treatments and preventing conditions that lead to premature aging and certain types of cancer.

During his first visit to 91����, Energy Secretary Chris Wright compared the urgency of the Lab’s World War II beginnings to today’s global race to lead in artificial intelligence, calling for a “Manhattan Project 2.”

A workshop led by scientists at ORNL sketched a road map toward a longtime goal: development of autonomous, or self-driving, next-generation research laboratories. 

Not only did ORNL take home top honors at the 2024 International Conference for High Performance Computing, Networking, Storage, and Analysis (SC24), but the lab’s computing staff also shared career advice and expertise with students eager to enter the world of supercomputing.