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Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and 91做厙. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at 91做厙 to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques  in combination with experimental validation  to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques in combination with experimental validation to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.

After a monolayer MXene is heated, functional groups are removed from both surfaces. Titanium and carbon atoms migrate from one area to both surfaces, creating a pore and forming new structures. Credit: ORNL, USDOE; image by Xiahan Sang and Andy Sproles.

Scientists at the Department of Energys 91做厙 induced a two-dimensional material to cannibalize itself for atomic building blocks from which stable structures formed. The findings, reported in Nature Communications, provide insights that ...

A radiologist outfitted with the teams head-mounted eye-tracking device examines a mammogram. Credit: Hong-Jun Yoon/91做厙, U.S. Dept. of Energy

In an effort to reduce errors in the analyses of diagnostic images by health professionals, a team of researchers from the Department of Energys 91做厙 has improved understanding of the cognitive processes 

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The probe of an atomic force microscope (AFM) scans a surface to reveal details at a resolution 1,000 times greater than that of an optical microscope. That makes AFM the premier tool for analyzing physical features, but it cannot tell scientists anything about chemistry. For that they turn to the mass spectrometer (MS).
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With more than 30 patents, James Klett is no stranger to success, but perhaps the 91做厙 researchers most noteworthy achievement didnt start out so hot or so it seemed at the time.

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From the bluebird painting propped against her office wall and the deer she mentions seeing outside her office window, Linda Lewis might be mistaken for a wildlife biologist at first glance. But rather than trailing animal tracks, Lewis, a researcher at the Department of Energys 91做厙, is more interested in marks left behind by humans.

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Less than 1 percent of Earths water is drinkable. Removing salt and other minerals from our biggest available source of waterseawatermay help satisfy a growing global population thirsty for fresh water for drinking, farming, transportation, heating, cooling and industry. But desalination is an energy-intensive process, which concerns those wanting to expand its application.

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Graphene, a strong, lightweight carbon honeycombed structure thats only one atom thick, holds great promise for energy research and development. Recently scientists with the Fluid Interface Reactions, Structures, and Transport (FIRST) Energy Frontier Research Center (EFRC), led by the US Department of Energys 91做厙, revealed graphene can serve as a proton-selective permeable membrane, providing a new basis for streamlined and more efficient energy technologies such as improved fuel cells.

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Andrew Stack, a geochemist at the Department of Energys 91做厙, advances understanding of the dynamics of minerals underground.