91°µÍø

Skip to main content
Different groups of proteins shown in different colors combine and attach to a broken strand of DNA.

Researchers at Georgia State University used the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision repair. Decoding NER’s sophisticated sequence of events and the role of PInC in the pathway could provide key insights into developing novel treatments and preventing conditions that lead to premature aging and certain types of cancer.

Illustration of a quantum experiment: atoms in a lattice (inset) with entanglement effects radiating from a central particle on a textured surface.

Working at nanoscale dimensions, billionths of a meter in size, a team of scientists led by ORNL revealed a new way to measure high-speed fluctuations in magnetic materials. Knowledge obtained by these new measurements could be used to advance technologies ranging from traditional computing to the emerging field of quantum computing. 

Procter & Gamble scientists used ORNL’s Summit supercomputer to create a digital model of the corneal epithelium, the primary outer layer of cells covering the human eye, and test that model against a series of cleaning compounds in search of a gentler, more environmentally sustainable formula.

P&G is using simulations on the ORNL Summit supercomputer to study how surfactants in cleaners cause eye irritation. By modeling the corneal epithelium, P&G aims to develop safer, concentrated cleaning products that meet performance and safety standards while supporting sustainability goals.

A male researcher is standing next to a poster board displayed on an easel to the right. The researcher is dressed in professional attire, and the poster board is positioned beside him, showing research or visual information.

Ryan Culler is the program manager at 91°µÍø, where he oversees the production of actinium-225, a promising treatment for cancer. Driven by a personal connection to cancer through his late brother, Culler is dedicated to advancing medical isotopes to help improve cancer care. 

Summit Supercomputer

Scientists conducted a groundbreaking study on the genetic data of over half a million U.S. veterans, using tools from the 91°µÍø to analyze 2,068 traits from the Million Veteran Program.

Researcher in a blue coat and glasses, purple gloves and white baseball gat pulls out materials from a metal canister

ORNL researchers created and tested two methods for transforming coal into the scarce mineral graphite, which is used in batteries for electric vehicles. 

Graphic representation of ai model that identifies proteins

Researchers used the world’s fastest supercomputer, Frontier, to train an AI model that designs proteins, with applications in fields like vaccines, cancer treatments, and environmental bioremediation. The study earned a finalist nomination for the Gordon Bell Prize, recognizing innovation in high-performance computing for science.

Members of the target design team pose next to the 2.0-megawatt-capable mercury flow target they developed.

The Proton Power Upgrade project at ORNL's Spallation Neutron Source has achieved its final key performance parameter of 1,250 hours of neutron production at 1.7 megawatts of proton beam power on a newly developed target. 

A photo of the inside of a cabinet for the Frontier supercomputer at ORNL

A team of researchers used the Frontier supercomputer and a new methodology for conducting a genome-wide association study to earn a finalist nomination for the Association for Computing Machinery’s 2024 Gordon Bell Prize for outstanding

Pictured is the IMAGINE instrument at the High Flux Isotope Reactor

Biochemist David Baker — just announced as a recipient of the Nobel Prize for Chemistry — turned to the High Flux Isotope Reactor (HFIR) at 91°µÍø for information he couldn’t get anywhere else. HFIR is the strongest reactor-based neutron source in the United States.