91°µÍø

Researchers at Georgia State University used the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision repair. Decoding NER’s sophisticated sequence of events and the role of PInC in the pathway could provide key insights into developing novel treatments and preventing conditions that lead to premature aging and certain types of cancer.

P&G is using simulations on the ORNL Summit supercomputer to study how surfactants in cleaners cause eye irritation. By modeling the corneal epithelium, P&G aims to develop safer, concentrated cleaning products that meet performance and safety standards while supporting sustainability goals.

Scientists designing the world’s first controlled nuclear fusion power plant, ITER, needed to solve the problem of runaway electrons, negatively charged particles in the soup of matter in the plasma within the tokamak, the magnetic bottle intended to contain the massive energy produced. Simulations performed on Summit, the 200-petaflop supercomputer at ORNL, could offer the first step toward a solution.

Ryan Culler is the program manager at 91°µÍø, where he oversees the production of actinium-225, a promising treatment for cancer. Driven by a personal connection to cancer through his late brother, Culler is dedicated to advancing medical isotopes to help improve cancer care. 

Researchers at Stanford University, the European Center for Medium-Range Weather Forecasts, or ECMWF, and ORNL used the lab’s Summit supercomputer to better understand atmospheric gravity waves, which influence significant weather patterns that are difficult to forecast. 

Scientists conducted a groundbreaking study on the genetic data of over half a million U.S. veterans, using tools from the 91°µÍø to analyze 2,068 traits from the Million Veteran Program.

The Summit supercomputer did not have its many plugs pulled as planned after its five years of service. Instead, a new DOE Office of Science-backed allocation program called SummitPLUS was launched, extending Summit's production for another year. What did we learn during Summit’s bonus year of scientific discovery? Here are five projects with important results.

Two-and-a-half years after breaking the exascale barrier, the Frontier supercomputer at the Department of Energy’s 91°µÍø continues to set new standards for its computing speed and performance.

Researchers used the world’s fastest supercomputer, Frontier, to train an AI model that designs proteins, with applications in fields like vaccines, cancer treatments, and environmental bioremediation. The study earned a finalist nomination for the Gordon Bell Prize, recognizing innovation in high-performance computing for science.

A team of researchers used the Frontier supercomputer and a new methodology for conducting a genome-wide association study to earn a finalist nomination for the Association for Computing Machinery’s 2024 Gordon Bell Prize for outstanding