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Different groups of proteins shown in different colors combine and attach to a broken strand of DNA.

Researchers at Georgia State University used the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision repair. Decoding NER’s sophisticated sequence of events and the role of PInC in the pathway could provide key insights into developing novel treatments and preventing conditions that lead to premature aging and certain types of cancer.

Neus Domingo Marimon, ORNL scientist, poses for a photo in black with hair down

Neus Domingo Marimon, leader of the Functional Atomic Force Microscopy group at the Center for Nanophase Materials Sciences of ORNL, has been elevated to senior member of the Institute of Electrical and Electronics Engineers.

Procter & Gamble scientists used ORNL’s Summit supercomputer to create a digital model of the corneal epithelium, the primary outer layer of cells covering the human eye, and test that model against a series of cleaning compounds in search of a gentler, more environmentally sustainable formula.

P&G is using simulations on the ORNL Summit supercomputer to study how surfactants in cleaners cause eye irritation. By modeling the corneal epithelium, P&G aims to develop safer, concentrated cleaning products that meet performance and safety standards while supporting sustainability goals.

Two pictures of a rounded triangle shape are shown in mirror image. The left is white with red and purple spots in the middle while the one on the right is purple with a yellow and blue ring in the middle

Scientists designing the world’s first controlled nuclear fusion power plant, ITER, needed to solve the problem of runaway electrons, negatively charged particles in the soup of matter in the plasma within the tokamak, the magnetic bottle intended to contain the massive energy produced. Simulations performed on Summit, the 200-petaflop supercomputer at ORNL, could offer the first step toward a solution.

Photo is a high aerial view of lake superior through the clouds

Researchers at Stanford University, the European Center for Medium-Range Weather Forecasts, or ECMWF, and ORNL used the lab’s Summit supercomputer to better understand atmospheric gravity waves, which influence significant weather patterns that are difficult to forecast. 

Chad sitting in a lab coat at a desk

Chad Parish, a senior researcher at ORNL, studies materials at the atomic level to improve nuclear reactors. His work focuses on fusion and fission energy, using microscopy and collaborating with experts to advance materials for extreme environments.

Summit Supercomputer

Scientists conducted a groundbreaking study on the genetic data of over half a million U.S. veterans, using tools from the 91°µÍø to analyze 2,068 traits from the Million Veteran Program.

Picture shows magnetic domains in uranium with a blue and orange organic shapes, similar to lava flowing through water, but in graphic form

The US focuses on nuclear nonproliferation, and ORNL plays a key role in this mission. The lab conducts advanced research in uranium science, materials analysis and nuclear forensics to detect illicit nuclear activities. Using cutting-edge tools and operational systems, ORNL supports global efforts to reduce nuclear threats by uncovering the history of nuclear materials and providing solutions for uranium removal. 

The summit supercomputer logo on a computer cabinet off center going to the left. There are 7 cabinets going off to the left.

The Summit supercomputer did not have its many plugs pulled as planned after its five years of service. Instead, a new DOE Office of Science-backed allocation program called SummitPLUS was launched, extending Summit's production for another year. What did we learn during Summit’s bonus year of scientific discovery? Here are five projects with important results.

Black computing cabinets in a row on a white floor in the data center that houses the Frontier supercomputer at 91°µÍø

Two-and-a-half years after breaking the exascale barrier, the Frontier supercomputer at the Department of Energy’s 91°µÍø continues to set new standards for its computing speed and performance.