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Scientists at ORNL have developed a first-ever method of detecting ribonucleic acid, or RNA, inside plant cells using a technique that results in a visible fluorescent signal. The technology can help researchers detect and track changes in RNA and gene expression in real time, providing a powerful tool for the development of hardier bioenergy and food crops and for detection of unwanted plant modifications, pathogens and pests.  

Researcher is sitting in bio lab surrounded with plants

Dave Weston studies how microorganisms influence plant health and stress tolerance, using the Advanced Plant Phenotyping Laboratory to accelerate research on plant-microbe interactions and develop resilient crops for advanced fuels, chemicals and materials.

A cargo ship to the left of the seaport with bright blue metal surrounding it

In collaboration with the U.S. Department of Homeland Security’s Science and Technology Directorate, researchers at ORNL are evaluating technology to detect compounds emitted by pathogens and pests in agricultural products at the nation’s border. 

Animated graphic with a plant on the right, blue sphere on the left and blue glowing dots scattered throughout.

To help reduce the likelihood of losing future cultivated crops to drought and other seasonal hardships, researchers from ORNL, Budapest and Hungary are using neutrons, light microscopy and transmission electron microscopy to study the 'Never Never' plant, known for its ability to endure periods of little to no rain. 

Different groups of proteins shown in different colors combine and attach to a broken strand of DNA.

Researchers at Georgia State University used the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision repair. Decoding NER’s sophisticated sequence of events and the role of PInC in the pathway could provide key insights into developing novel treatments and preventing conditions that lead to premature aging and certain types of cancer.

Secretary Wright leans over red computer door, signing with silver sharpie as ORNL Director Stephen Streiffer looks on

During his first visit to 91°µÍø, Energy Secretary Chris Wright compared the urgency of the Lab’s World War II beginnings to today’s global race to lead in artificial intelligence, calling for a “Manhattan Project 2.â€

Illustration of a quantum experiment: atoms in a lattice (inset) with entanglement effects radiating from a central particle on a textured surface.

Working at nanoscale dimensions, billionths of a meter in size, a team of scientists led by ORNL revealed a new way to measure high-speed fluctuations in magnetic materials. Knowledge obtained by these new measurements could be used to advance technologies ranging from traditional computing to the emerging field of quantum computing. 

This is an image of a photon chip, it's a black background with green squiggle lines across it, with two blue lines running horizontally in the middle with an inch in between.

Quantum information scientists at ORNL successfully demonstrated a device that combines key quantum photonic capabilities on a single chip for the first time.

Hugh O'Neil, director or ORNL's Center for Structural Molecular Biology is sitting in the lab on a stool, hand on desk with glasses on. There are lab related items blurred in the foreground.

Hugh O’Neill’s lifelong fascination with the complexities of the natural world drives his research at ORNL, where he’s using powerful neutron beams to dive deep into the microscopic realm of biological materials and unlock secrets for better production of domestic biofuels and bioproducts.

Close up image of Quantum Science Center poster with the QSC logo.

Registration for the Quantum Science Center’s Summer School is open now through Feb. 28, 2025. Conducted in partnership with the Quantum Science Center at ORNL, this year’s summer school will be hosted at the Purdue Quantum Science and Engineering Institute Apr. 21 through Apr. 25, 2025, on the Purdue University campus.