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Scientists at ORNL have developed a first-ever method of detecting ribonucleic acid, or RNA, inside plant cells using a technique that results in a visible fluorescent signal. The technology can help researchers detect and track changes in RNA and gene expression in real time, providing a powerful tool for the development of hardier bioenergy and food crops and for detection of unwanted plant modifications, pathogens and pests.
Scientists at ORNL and the University of Cincinnati achieved a breakthrough in understanding the vulnerability of microbes to the butanol they produce during fermentation of plant biomass. The discovery could pave the way for more efficient production of domestic fuels, chemicals and materials.

In collaboration with the U.S. Department of Homeland Security’s Science and Technology Directorate, researchers at ORNL are evaluating technology to detect compounds emitted by pathogens and pests in agricultural products at the nation’s border.

By editing the polymers of discarded plastics, ORNL chemists have found a way to generate new macromolecules with more valuable properties than those of the starting material.

P&G is using simulations on the ORNL Summit supercomputer to study how surfactants in cleaners cause eye irritation. By modeling the corneal epithelium, P&G aims to develop safer, concentrated cleaning products that meet performance and safety standards while supporting sustainability goals.

Benjamin Manard, a nuclear analytical chemist at ORNL, has been named the 2025 winner of the Emerging Leader in Atomic Spectroscopy Award from Spectroscopy magazine.

The US focuses on nuclear nonproliferation, and ORNL plays a key role in this mission. The lab conducts advanced research in uranium science, materials analysis and nuclear forensics to detect illicit nuclear activities. Using cutting-edge tools and operational systems, ORNL supports global efforts to reduce nuclear threats by uncovering the history of nuclear materials and providing solutions for uranium removal.

ORNL researchers created and tested two methods for transforming coal into the scarce mineral graphite, which is used in batteries for electric vehicles.

A team of scientists with two Department of Energy Bioenergy Research Centers — the Center for Bioenergy Innovation at 91°µÍø and the Center for Advanced Bioenergy and Bioproducts Innovation at the University of Illinois Urbana-Champaign — identified a gene in a poplar tree that enhances photosynthesis and can boost tree height by about 30% in the field and by as much as 200% in the greenhouse.

A chemical reaction can convert two polluting greenhouse gases into valuable building blocks for cleaner fuels and feedstocks, but the high temperature required for the reaction also deactivates the catalyst. A team led by ORNL has found a way to thwart deactivation. The strategy may apply broadly to other catalysts.