Andrii Y Kovalevskyi Distinguished R&D Scientist Contact 505.310.4184 | KOVALEVSKYAY@ORNL.GOV All Publications Pyridoxal 5′-phosphate dependent reactions: Analyzing the mechanism of aspartate aminotransferase Protein kinase A in the neutron beam: Insights for catalysis from directly observing protons First Experiments New Science Opportunities at the Spallation Neutron Source Second Target Station (abridged) Pressure and Temperature Effects on the Formation of Aminoacrylate Intermediates of Tyrosine Phenol-lyase Demonstrate Reaction Dynamics First Experiments: New Science Opportunities at the Spallation Neutron Source Second Target Station... A new crystal form of human acetylcholinesterase for exploratory room-temperature crystallography studies Productive reorientation of a bound oxime reactivator revealed in room temperature X-ray structures of native and VX-inhibited human acetylcholinesterase Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex Temperature-Induced Replacement of Phosphate Proton with Metal Ion Captured in Neutron Structures of A-DNA Neutron scattering in the biological sciences: progress and prospects The Neutron Macromolecular Crystallography Instruments at 91°µÍø: Advances, Challenges, and Opportunities A suite-level review of the neutron single-crystal diffraction instruments at 91°µÍø Understanding the pH-Dependent Reaction Mechanism of a Glycoside Hydrolase Using High-Resolution X-ray and Neutron Crystallography Hyperconjugation Promotes Catalysis in a Pyridoxal 5′-Phosphate-Dependent Enzyme "To Be or Not to Be" Protonated: Atomic Details of Human Carbonic Anhydrase-Clinical Drug Complexes by Neutron Crystallography and Simulation "To Be or Not to Be" Protonated: Atomic Details of Human Carbonic Anhydrase-Clinical Drug Complexes by Neutron Crystallography and Simulation Direct visualization of critical hydrogen atoms in a pyridoxal 5′-phosphate enzyme Mannobiose Binding Induces Changes in Hydrogen Bonding and Protonation States of Acidic Residues in Concanavalin A As Reveale... Biological Structures Neutron and Atomic Resolution X-ray Structures of a Lytic Polysaccharide Monooxygenase Reveal Copper-Mediated Dioxygen Binding and Evidence for N-Terminal Deprotonation Direct Evidence That an Extended Hydrogen-Bonding Network Influences Activation of Pyridoxal 5’- Phosphate in Aspartate Aminotransferase Room temperature neutron crystallography of drug resistant HIV-1 protease uncovers limitations of X-ray structural analysis at 100K Neutron structures of the Helicobacter pylori 5′-methylthioadenosine nucleosidase highlight proton sharing and protonation states Direct visualization of critical hydrogen atoms in a pyridoxal 5′-phosphate enzyme Neutron/X-ray Joint Refinement of The Active and Inactive Form of Helicobacter pylori 5'-Methylthioadenosine Nucleosidase... Pagination First page « First Previous page ‹â¶Ä¹ … Page 2 Current page 3 Page 4 Next page ›â¶Äº Last page Last » Key Links Curriculum Vitae Organizations User Facilities
