Hugh O'Neill Group Leader, Biological Labeling and Scattering Contact ONEILLHM@ORNL.GOV All Publications Malleability of the SARS-CoV-2 3CL Mpro Active-Site Cavity Facilitates Binding of Clinical Antivirals Unusual zwitterionic catalytic site of SARS–CoV-2 main protease revealed by neutron crystallography... Model-based Reconstruction for Single Particle Cryo-Electron Microscopy Room-temperature X-ray crystallography reveals the oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL Mpro: insights into enzyme mechanism and drug design Structural Insights into Low and High Recalcitrance Natural Poplar Variants Using Neutron and X-ray Scattering Deconstruction of biomass enabled by local demixing of cosolvents at cellulose and lignin surfaces... Effects of soil particles and convective transport on dispersion and aggregation of nanoplastics via small-angle neutron scattering (SANS) and ultra SANS (USANS) Deconstruction of biomass enabled by local demixing of cosolvents at cellulose and lignin surfaces Structural plasticity of SARS-CoV-2 3CL Mpro active site cavity revealed by room temperature X-ray crystallography Ammonia-salt solvent promotes cellulosic biomass deconstruction under ambient pretreatment conditions to enable rapid soluble sugar production at ultra-low enzyme loadings Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer Generation of the configurational ensemble of an intrinsically disordered protein from unbiased molecular dynamics simulation Interaction of Zinc Oxide Nanoparticles with Water: Implications for Catalytic Activity Mechanical formation of micro- and nano-plastic materials for environmental studies in agricultural ecosystems Production of deuterated biomass by cultivation of Lemna minor (duckweed) in D2O Structural Studies of Deuterium-Labeled Switchgrass Biomass Arabinose substitution effect on xylan rigidity and self-aggregation Neutron scattering in the biological sciences: progress and prospects Observation of a structural gradient in Winsor-III microemulsion systems Impact of hydration and temperature history on the structure and dynamics of lignin Tension wood structure and morphology conducive for better enzymatic digestion Protein extraction into the bicontinuous microemulsion phase of a Water/SDS/pentanol/dodecane winsor-III system: Effect on nanostructure and protein conformation Dynamics of water bound to crystalline cellulose Dynamical Transition of Collective Motions in Dry Proteins Nanoscopic dynamics of bicontinous microemulsions: effect of membrane associated protein Pagination First page « First Previous page ‹â¶Ä¹ Page 1 Current page 2 Page 3 … Next page ›â¶Äº Last page Last » Key Links Curriculum Vitae Organizations User Facilities Center for Structural Molecular Biology
