Michael R Garvin Staff Scientist Contact garvinmr@ornl.gov All Publications Multiomic Network Analysis Identifies Dysregulated Neurobiological Pathways in Opioid Addiction Analyses of GWAS signal using GRIN identify additional genes contributing to suicidal behavior Novel Mito-Nuclear Combinations Facilitate the Global Invasion of a Major Agricultural Crop Pest High dimensional predictions of suicide risk in 4.2 million US Veterans using ensemble transfer learning Using iterative random forest to find geospatial environmental and Sociodemographic predictors of suicide attempts... Plasma proteomics of SARS-CoV-2 infection and severity reveals impact on Alzheimer’s and coronary disease pathways Structural variants identified using non-Mendelian inheritance patterns advance the mechanistic understanding of autism spectrum disorder Genetics of varicose veins reveals polygenic architecture and genetic overlap with arterial and venous disease Structural and functional characterization of NEMO cleavage by SARS-CoV-2 3CLpro Antiviral Strategies Against SARS-CoV-2: A Systems Biology Approach A genome-wide association study of suicide attempts in the million veterans program identifies evidence of pan-ancestry and ancestry-specific risk loci NF-κB perturbation reveals unique immunomodulatory functions in Prx1+ fibroblasts that promote development of atopic dermatitis Response to comment on ‘SARS-CoV-2 suppresses anticoagulant and fibrinolytic gene expression in the lung’ A k-mer based approach for classifying viruses without taxonomy identifies viral associations in human autism and plant microbiomes SARS-CoV-2 suppresses anticoagulant and fibrinolytic gene expression in the lung Potentially adaptive SARS-CoV-2 mutations discovered with novel spatiotemporal and explainable AI models Potential pathogenicity determinants identified from structural proteomics of SARS-CoV and SARS-CoV-2 A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm Can exascale computing and explainable artificial intelligence applied to plant biology deliver on the United Nations sustain... Key Links Curriculum Vitae
