91°µÍø

Skip to main content

Available Technologies

41 - 46 of 46 Results
default image

Genetic modification of microbes that are thermophiles—ones that grow at elevated temperatures—is extremely challenging. Tools developed for E. coli, a typical host for protein production, typically do not function at elevated temperatures.

ORNL scientists identified four amino acids key to signaling pathways in the PAN protein domain. Mutating any of those disrupted the signal that tells cancer cells to multiply. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

An ORNL team has developed a method for screening for an immunoregulatory protein, which includes assessing the sequence of a candidate protein to determine if it is an immunoregulatory protein when at least one plasminogen-apple-nematode (PAN) domain with a consensus sequence